Human Long-R3-IGF-I is an analog of human IGF-I that has been engineered to increase biological activity. It is significantly more potent than human IGF-I in vitro due to decreased binding to IGF binding proteins. The recombinant human Long-R3-IGF-I has a calculated molecular mass of 9111Da and is expressed in E. coli. It is available in 100μg/vial, 500μg/vial, and 1mg/vial formulations and should be stored at 2-8oC for two years or -20oC for long term storage. Quality control tests show that it has a purity of >95% by RP-HPLC analysis and >98% by SDS-PAGE analysis, and a specific activity of 1.0×106 IU/mg as determined by the dose-dependant proliferation of murine BALBC 3T3 cells. Endotoxin levels are less than 1.0 EU per mg as determined by the LAL method.
Recombinant human Follistatin isoform 2 is a polypeptide chain containing 217 amino acids with a predicted molecular mass of 32.3 kDa. Follistatin is a monomeric glycoprotein that binds to ligands of the TGF-β superfamily and regulates their activity. The biological activity of human Growth Hormone is measured by cell proliferation using Nb2-11 cells with an ED50 of 0.1-0.3 ug/ml in the presence of 7.5 ng/ml Activin A.
Follastatin 344 is a naturally occurring human peptide and a potent inhibitor of myostatin. It is being studied for its role in regulation of muscle growth, as an antagonist to myostatin. It is also being investigated for its involvement in polycystic ovary syndrome (PCOS). The suggested dosage for muscle building protocol is 0.1mL daily for 10 days and for fat loss protocol is 0.1ml once weekly for 10 weeks.
В данном списке представлены препараты, их названия, состав и некоторые характеристики. Среди них есть препараты для лечения гормональных нарушений, сердечно-сосудистых заболеваний, а также косметические препараты. Каждый препарат содержит информацию о его составе, включая название и количество компонентов.
Список продуктов для медицинского применения, включающий в себя названия и кас-номера 47 препаратов, таких как Abarelix Acetate, Angiotensin Acetate, Gonadorelin Acetate и другие.
This page lists the molecular formulas and sequences of various peptides, including antagonists, antiestrogens, and neurotrophic peptides. It also includes information on peptide assays and binding fragments.
В данном списке представлены названия и характеристики 44 препаратов для медицинского применения, включая их английские и китайские названия, чистоту, CAS-номер и другие параметры.
Melanocyte-inhibiting factor (MIF-1) is a peptide fragment derived from oxytocin that produces multiple effects, including blocking opioid receptor activation, acting as a positive allosteric modulator of dopamine receptor subtypes, inhibiting release of neuropeptides, and potentiating melatonin activity. MIF-1 has been investigated for its antidepressant, nootropic, and anti-Parkinsonian effects and is resistant to metabolism in the bloodstream. Other related peptides include Tyr-MIF-1 and endomorphin-1 and -2.
This study aimed to test the hypothesis that a new myostatin inhibitor, a recombinant myostatin propeptide, can enhance the repair and regeneration of both muscle and bone in cases of deep penetrant injury. The study used a fibula osteotomy model with associated damage to lateral compartment muscles in mice. The results showed that blocking active myostatin with systemic injections of a recombinant myostatin propeptide improved muscle and bone repair.