Follastatin 344 (& 315) - Potent Myostatin Inhibitor Purity: 98% (HPLC on request)
Sequence: 344 & 315 Amino Acid variations available
Follastatin 344 & 315
Description
Follistatin 344 is a naturally occurring human peptide and a potent inhibitor of myostatin. Myostatin
encourages the degradation of myotubes (skeletal muscle fibers) therefore inhibition of myostatin will
ultimately result in increased muscle mass by preventing degradation.
Follistatin is being studied for its role in regulation of muscle growth, as an antagonist to myostatin (also
known as GDF-8, a TGF superfamily member). Lee & McPherron demonstrated that inhibition of GDF-
8, either by genetic elimination (knockout) or by increasing the amount of follistatin, resulted in greatly
increased muscle mass.
In 2009, research with macaque monkeys demonstrated that regulating follistatin via gene therapy also
resulted in muscle growth and increases in strength.
A study has also shown that increased levels of follistatin, by leading to increased muscle mass of certain
core muscular groups, can increase life expectancy in cases of spinal muscular atrophy (SMA) in animal
models.
It is also being investigated for its involvement in polycystic ovary syndrome (PCOS), though there is
debate as to its direct role in this infertility disease.
Protocol
Content and Potency: 1000mcg/mL x 1mL
Suggested dosage: 0.1mL daily for 10 days MUSCLE BUILDING PROTOCOL
0.1ml once weekly for 10 weeks FAT LOSS PROTOCOL
Suggested Protocol: 0.1mL daily for 5 days then 0.1mL once weekly